Pharmacokinetics of oral doxycycline during combination treatment of severe falciparum malaria.

نویسندگان

  • Paul N Newton
  • Jean-François Chaulet
  • Alan Brockman
  • Wirongrong Chierakul
  • Arjen Dondorp
  • Ronatrai Ruangveerayuth
  • Sornchai Looareesuwan
  • Cyril Mounier
  • Nicholas J White
چکیده

The pharmacokinetics of oral doxycycline administered at 200 mg every 24 h were investigated in 17 patients recovering from severe Plasmodium falciparum malaria. The data suggest that the doses of doxycycline currently recommended (circa 3.5 mg/kg of body weight daily) may not be optimal.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 49 4  شماره 

صفحات  -

تاریخ انتشار 2005